Collected Datasets

A collected (study-specific) dataset holds metadata about the variables collected within a data collection event.

357 Collected Datasets

Acronym Name Description
LLS_G2_T1_Cellcounts LLS G2 T1 Cellcounts None
LLS_G3_T4_Castor_Balance_tests Castor Balance tests None
LLS_G3_T4_Castor_Blood_sampling Castor Blood sampling None
LLS_G3_T4_Castor_Cognitive_tests Castor Cognitive tests None
LLS_G3_T4_Castor_Medication_use Castor Medication use None
LLS_G3_T4_Castor_Medical_history_CCI Castor Medical history CCI None
LLS_G3_T4_Castor_Measurements_General Castor Measurements General None
LLS_G3_T4_Castor_Measurements_BIA_measurement Castor Measurements BIA measurement None
LLS_G3_T4_Castor_Measurements_Blood_pressure Castor Measurements Blood pressure None
LLS_G3_T4_Castor_Measurements_ECG Castor Measurements ECG None
LLS_G3_T4_Castor_Measurements_Grip_strength_test Castor Measurements Grip strength test None
LLS_G3_T4_Castor_Measurements_Lung_function Castor Measurements Lung function None
LLS_G3_T4_Castor_Scores_questionnaire_accidental Castor Scores questionnaire accidental None
LLS_G3_T4_Castor_Home_biomaterial Castor Home biomaterial None
LLS_G3_T4_Castor_Home_questionnaires Castor Home questionnaires None
LLS_G3_T4_Castor_Welcome Castor Welcome None
LLS_G2_T1_GutMicroBiomeRelated LLS G2 T1 GutMicroBiomeRelated None
LLS_G3_Q1_FFQ_Fooditems LLS G3 Q1 FFQ Fooditems None
LLS_G3_T4_Nightingale_2024 Nightingale 2024 None
LLS_G3_T4_survey_General_questionnaire_LLS survey General questionnaire LLS None
LLS_G3_T4_survey_Gastrointestinal_health_(GSRS) survey Gastrointestinal health (GSRS) None
LLS_G3_T4_survey_Physical_activity_(SQUASH)_OLD survey Physical activity (SQUASH) OLD None
LLS_G3_T4_survey_Physical_activity_(SQUASH) survey Physical activity (SQUASH) None
LLS_G3_T4_survey_Physical_function_ADL_IADL survey Physical function ADL IADL None
LLS_G3_T4_survey_Mood_and_behavior_(CES-D) survey Mood and behavior (CES-D) None
LLS_G3_T4_survey_Quality_of_life_(EQ-5D) survey Quality of life (EQ-5D) None
LLS_G3_T4_survey_Life_orientation_questionnaire survey Life orientation questionnaire None
LLS_G3_T4_Bloodcellcounts Bloodcellcounts None
LLS_G3_T4_survey_Food_frequency_questionnaire_(FFQ) survey Food frequency questionnaire (FFQ) None
LLS_G2_T1_NightingaleQL2020 LLS G2 T1 NightingaleQL2020 None
LLS_G3_T1_Blood_cellcounts LLS G3 T1 Blood cellcounts None
LLS_G3_T1_ClinicalChemistry LLS G3 T1 ClinicalChemistry None
LLS_G3_T1_Demography2024 LLS G3 T1 Demography2024 None
LLS_G3_T1_LeidenNMR_Kimble LLS G3 T1 LeidenNMR Kimble None
LLS_G3_T1_Nightingale_QL2020 LLS G3 T1 Nightingale QL2020 None
LLS_G3_T1_Participant_info LLS G3 T1 Participant info None
LLS_G2_T1_clinicalchemistry LLS G2 T1 clinicalchemistry None
LLS_G3_T2_Participant_info LLS G3 T2 Participant info None
LLS_G3_T2_BIA_Body_Composition LLS G3 T2 BIA Body Composition None
LLS_G3_T2_blood_pressure LLS G3 T2 blood pressure None
LLS_G3_T2_Clinical_chemistry LLS G3 T2 Clinical chemistry None
LLS_G3_T2_Gripstrength LLS G3 T2 Gripstrength None
LLS_G3_T2_Nightingale_QL16_20 LLS G3 T2 Nightingale QL16 20 None
LLS_G3_T3_Apolipoprotein_pltf LLS G3 T3 Apolipoprotein pltf None
LLS_G3_T3_Nightingale_QL16_20 LLS G3 T3 Nightingale QL16 20 None
LLS_G3_T3_OLINKcardiomatebolic_measures LLS G3 T3 OLINKcardiomatebolic measures None
LLS_G3_T3_OLINKcardiomatebolic_metadata LLS G3 T3 OLINKcardiomatebolic metadata None
LLS_G3_T3_OLINKcardiomatebolic_samples LLS G3 T3 OLINKcardiomatebolic samples None
LLS_G3_T3_Participant_info LLS G3 T3 Participant info None
LLS_G3_T3_Cognition_questions LLS G3 T3 Cognition questions None
LLS_G3_T3_Global_Metabolomics LLS G3 T3 Global Metabolomics None
LLS_G3_T3_Global_Metabolomics_Dictionary LLS G3 T3 Global Metabolomics Dictionary None
LLS_G3_T3_Global_Metabolomics_Overview LLS G3 T3 Global Metabolomics Overview None
LLS_G3_T3_IGF_axis LLS G3 T3 IGF axis None
LLS_G3_T3_MRI_Data LLS G3 T3 MRI Data None
LLS_G3_T3_Plasma_Amyloid_markers LLS G3 T3 Plasma Amyloid markers None
LLS_G3_T3_Plasma_endothelial_mrk LLS G3 T3 Plasma endothelial mrk None
LLS_G3_T3_SignalingLipids_Dictionary LLS G3 T3 SignalingLipids Dictionary None
LLS_G3_T3_SignalingLipids_Metabolomics LLS G3 T3 SignalingLipids Metabolomics None
LLS_G3_T3_SignalingLipids_Overview LLS G3 T3 SignalingLipids Overview None
LLS_G3_T3_Thyroid_measures LLS G3 T3 Thyroid measures None
LLS_G3_Q1_FFQ_Aminoacids LLS G3 Q1 FFQ Aminoacids None
LLS_G3_Q1_FFQ_Food_group_key LLS G3 Q1 FFQ Food group key None
LLS_G3_Q1_FFQ_Foodgroups_main LLS G3 Q1 FFQ Foodgroups main None
LLS_G3_Q1_FFQ_Foodgroups_sub LLS G3 Q1 FFQ Foodgroups sub None
LLS_G3_Q1_FFQ_key_food_groups_20200911 LLS G3 Q1 FFQ key food groups 20200911 None
LLS_G3_Q1_FFQ_Macronutrients LLS G3 Q1 FFQ Macronutrients None
LLS_G3_Q1_FFQ_Nevo2006 LLS G3 Q1 FFQ Nevo2006 None
LLS_G2_T1_NMR LLS G2 T1 NMR None
LLS_G2_T1_Participant_info LLS G2 T1 Participant info None
LLS_G2_T1_Visit_Measures LLS G2 T1 Visit Measures None
LLS_G2_T1_Demography LLS G2 T1 Demography None
LLS_G2_T1_LipoScience LLS G2 T1 LipoScience None
LLS_G2_T1_Demography2021 LLS G2 T1 Demography2021 None
LLS_G2_T1_SHARK_data LLS G2 T1 SHARK data None
LLS_G3_T1_Demography2021 LLS G3 T1 Demography2021 None
LLS_G3_T1_SHARK_data LLS G3 T1 SHARK data None
LLS_G3_T1_Epigenetic_predictors LLS G3 T1 Epigenetic predictors None
LLS_G3_T1_IgG_LC-MS LLS G3 T1 IgG LC-MS None
LLS_G3_T1_LipoScience LLS G3 T1 LipoScience None
MetC_T0_MMSE MetC_T0_MMSE Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test ...
MetC_T0_SQUASH MetC_T0_SQUASH The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, ...
MetC_T0_Anthropometrics MetC_T0_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MetC_T0_eGFR MetC_T0_eGFR Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from ...
MetC_T0_Eligibility MetC_T0_Eligibility Participant eligibility for the study was determined based on medical criteria, functional ...
MetC_T0_InExClusion MetC_T0_InExClusion A checklist was used to capture all inclusion and exclusion criteria and verify that ...
MetC_T0_ParticipantInfo MetC_T0_ParticipantInfo Basic participant characteristics were collected using standardized study questionnaires and ...
MetC_T0_Questionnaire MetC_T0_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
MetC_T1_DEXAAssessment MetC_T1_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
MetC_T1_GSRS MetC_T1_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
MetC_T1_PSQI MetC_T1_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
MetC_T1_SF36v2NL MetC_T1_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
MetC_T1_SFsarQoL MetC_T1_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
MetC_T1_Anthropometrics MetC_T1_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MetC_T1_AtHome MetC_T1_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
MetC_T1_Base1RM MetC_T1_Base1RM Maximal muscle strength was assessed at baseline using one-repetition maximum testing on ...
MetC_T1_BloodSampling MetC_T1_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
MetC_T1_Fam1RM MetC_T1_Fam1RM Participants completed a familiarization session to learn correct exercise technique and become ...
MetC_T1_PhysicalFunction MetC_T1_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
MetC_T1_Questionnaire MetC_T1_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
MetC_T1_1RM MetC_T1_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
MetC_T1_Nutrition MetC_T1_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
MetC_T1_DEXA MetC_T1_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
MetC_T1_Nightingale MetC_T1_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
MetC_T1_GlucoseInsulinVitD MetC_T1_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
MetC_T2_DEXAAssessment MetC_T2_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
MetC_T2_GSRS MetC_T2_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
MetC_T2_PSQI MetC_T2_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
MetC_T2_SF36v2NL MetC_T2_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
MetC_T2_SFsarQoL MetC_T2_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
MetC_T2_Anthropometrics MetC_T2_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MetC_T2_AtHome MetC_T2_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
MetC_T2_BloodSampling MetC_T2_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
MetC_T2_1RM MetC_T2_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
MetC_T2_PhysicalFunction MetC_T2_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
MetC_T2_Uni1RM MetC_T2_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
MetC_T2_Nutrition MetC_T2_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
MetC_T2_DEXA MetC_T2_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
MetC_T2_Nightingale MetC_T2_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
MetC_T2_GlucoseInsulinVitD MetC_T2_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
MetC_dropouts_T0_MMSE MetC_dropouts_T0_MMSE Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test ...
MetC_dropouts_T0_SQUASH MetC_dropouts_T0_SQUASH The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, ...
MetC_dropouts_T0_Anthropometrics MetC_dropouts_T0_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MetC_dropouts_T0_eGFR MetC_dropouts_T0_eGFR Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from ...
MetC_dropouts_T0_Eligibility MetC_dropouts_T0_Eligibility Participant eligibility for the study was determined based on medical criteria, functional ...
MetC_dropouts_T0_InExClusion MetC_dropouts_T0_InExClusion A checklist was used to capture all inclusion and exclusion criteria and verify that ...
MetC_dropouts_T0_ParticipantInfo MetC_dropouts_T0_ParticipantInfo Basic participant characteristics were collected using standardized study questionnaires and ...
MetC_dropouts_T0_Questionnaire MetC_dropouts_T0_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
MetC_dropouts_T1_DEXAAssessment MetC_dropouts_T1_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
MetC_dropouts_T1_GSRS MetC_dropouts_T1_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
MetC_dropouts_T1_PSQI MetC_dropouts_T1_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
MetC_dropouts_T1_SF36v2NL MetC_dropouts_T1_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
MetC_dropouts_T1_SFsarQoL MetC_dropouts_T1_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
MetC_dropouts_T1_Anthropometrics MetC_dropouts_T1_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MetC_dropouts_T1_AtHome MetC_dropouts_T1_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
MetC_dropouts_T1_1RM MetC_dropouts_T1_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
MetC_dropouts_T1_BloodSampling MetC_dropouts_T1_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
MetC_dropouts_T1_Fam1RM MetC_dropouts_T1_Fam1RM Participants completed a familiarization session to learn correct exercise technique and become ...
MetC_dropouts_T1_PhysicalFunction MetC_dropouts_T1_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
MetC_dropouts_T1_Questionnaire MetC_dropouts_T1_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
MetC_dropouts_T1_Nutrition MetC_dropouts_T1_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
MetC_dropouts_T1_DEXA MetC_dropouts_T1_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
MetC_dropouts_T1_GlucoseInsulinVitD MetC_dropouts_T1_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
MobC_T0_MMSE MobC_T0_MMSE Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test ...
MobC_T0_SQUASH MobC_T0_SQUASH The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, ...
MobC_T0_Anthropometrics MobC_T0_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MobC_T0_eGFR MobC_T0_eGFR Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from ...
MobC_T0_Eligibility MobC_T0_Eligibility Participant eligibility for the study was determined based on medical criteria, functional ...
MobC_T0_InExClusion MobC_T0_InExClusion A checklist was used to capture all inclusion and exclusion criteria and verify that ...
MobC_T0_ParticipantInfo MobC_T0_ParticipantInfo Basic participant characteristics were collected using standardized study questionnaires and ...
MobC_T0_Questionnaire MobC_T0_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
MobC_T1_DEXAAssessment MobC_T1_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
MobC_T1_GSRS MobC_T1_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
MobC_T1_PSQI MobC_T1_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
MobC_T1_SF36v2NL MobC_T1_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
MobC_T1_SFsarQoL MobC_T1_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
MobC_T1_Anthropometrics MobC_T1_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MobC_T1_AtHome MobC_T1_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
MobC_T1_1RM MobC_T1_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
MobC_T1_BloodSampling MobC_T1_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
MobC_T1_Fam1RM MobC_T1_Fam1RM Participants completed a familiarization session to learn correct exercise technique and become ...
MobC_T1_PhysicalFunction MobC_T1_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
MobC_T1_Questionnaire MobC_T1_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
MobC_T1_Uni1RM MobC_T1_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
MobC_T1_Nutrition MobC_T1_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
MobC_T1_DEXA MobC_T1_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
MobC_T1_Nightingale MobC_T1_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
MobC_T1_GlucoseInsulinVitD MobC_T1_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
MobC_T2_DEXAAssessment MobC_T2_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
MobC_T2_GSRS MobC_T2_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
MobC_T2_PSQI MobC_T2_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
MobC_T2_SF36v2NL MobC_T2_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
MobC_T2_SFsarQoL MobC_T2_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
MobC_T2_Anthropometrics MobC_T2_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MobC_T2_AtHome MobC_T2_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
MobC_T2_BloodSampling MobC_T2_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
MobC_T2_1RM MobC_T2_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
MobC_T2_PhysicalFunction MobC_T2_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
MobC_T2_Uni1RM MobC_T2_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
MobC_T2_Nutrition MobC_T2_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
MobC_T2_DEXA MobC_T2_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
MobC_T2_Nightingale MobC_T2_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
MobC_T2_GlucoseInsulinVitD MobC_T2_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
MobC_dropouts_T0_MMSE MobC_dropouts_T0_MMSE Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test ...
MobC_dropouts_T0_SQUASH MobC_dropouts_T0_SQUASH The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, ...
MobC_dropouts_T0_Anthropometrics MobC_dropouts_T0_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MobC_dropouts_T0_eGFR MobC_dropouts_T0_eGFR Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from ...
MobC_dropouts_T0_Eligibility MobC_dropouts_T0_Eligibility Participant eligibility for the study was determined based on medical criteria, functional ...
MobC_dropouts_T0_InExClusion MobC_dropouts_T0_InExClusion A checklist was used to capture all inclusion and exclusion criteria and verify that ...
MobC_dropouts_T0_ParticipantInfo MobC_dropouts_T0_ParticipantInfo Basic participant characteristics were collected using standardized study questionnaires and ...
MobC_dropouts_T0_Questionnaire MobC_dropouts_T0_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
MobC_dropouts_T1_DEXAAssessment MobC_dropouts_T1_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
MobC_dropouts_T1_GSRS MobC_dropouts_T1_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
MobC_dropouts_T1_PSQI MobC_dropouts_T1_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
MobC_dropouts_T1_SF36v2NL MobC_dropouts_T1_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
MobC_dropouts_T1_SFsarQol MobC_dropouts_T1_SFsarQol This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
MobC_dropouts_T1_Anthropometrics MobC_dropouts_T1_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
MobC_dropouts_T1_AtHome MobC_dropouts_T1_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
MobC_dropouts_T1_1RM MobC_dropouts_T1_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
MobC_dropouts_T1_BloodSampling MobC_dropouts_T1_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
MobC_dropouts_T1_Fam1RM MobC_dropouts_T1_Fam1RM Participants completed a familiarization session to learn correct exercise technique and become ...
MobC_dropouts_T1_PhysicalFunction MobC_dropouts_T1_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
MobC_dropouts_T1_Questionnaire MobC_dropouts_T1_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
MobC_dropouts_T1_Uni1RM MobC_dropouts_T1_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
MobC_dropouts_T1_Nutrition MobC_dropouts_T1_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
MobC_dropouts_T1_DEXA MobC_dropouts_T1_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
MobC_dropouts_T1_GlucoseInsulinVitD MobC_dropouts_T1_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
REF_T0_MMSE REF_T0_MMSE Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test ...
REF_T0_SQUASH REF_T0_SQUASH The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, ...
REF_T0_Anthropometrics REF_T0_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
REF_T0_eGFR REF_T0_eGFR Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from ...
REF_T0_Eligibility REF_T0_Eligibility Participant eligibility for the study was determined based on medical criteria, functional ...
REF_T0_InExClusion REF_T0_InExClusion A checklist was used to capture all inclusion and exclusion criteria and verify that ...
REF_T0_ParticipantInfo REF_T0_ParticipantInfo Basic participant characteristics were collected using standardized study questionnaires and ...
REF_T0_Questionnaire REF_T0_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
REF_T1_DEXAAssessment REF_T1_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
REF_T1_GSRS REF_T1_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
REF_T1_PSQI REF_T1_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
REF_T1_SF36v2NL REF_T1_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
REF_T1_SFsarQoL REF_T1_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
REF_T1_Anthropometrics REF_T1_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
REF_T1_AtHome REF_T1_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
REF_T1_1RM REF_T1_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
REF_T1_BloodSampling REF_T1_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
REF_T1_Fam1RM REF_T1_Fam1RM Participants completed a familiarization session to learn correct exercise technique and become ...
REF_T1_PhysicalFunction REF_T1_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
REF_T1_Questionnaire REF_T1_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
REF_T1_Uni1RM REF_T1_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
REF_T1_Nutrition REF_T1_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
REF_T1_DEXA REF_T1_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
REF_T1_Nightingale REF_T1_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
REF_T1_GlucoseInsulinVitD REF_T1_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
TKRS_T0_MMSE TKRS_T0_MMSE Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test ...
TKRS_T0_SQUASH TKRS_T0_SQUASH The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, ...
TKRS_T0_Anthropometrics TKRS_T0_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
TKRS_T0_eGFR TKRS_T0_eGFR Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from ...
TKRS_T0_Eligibility TKRS_T0_Eligibility Participant eligibility for the study was determined based on medical criteria, functional ...
TKRS_T0_InExClusion TKRS_T0_InExClusion A checklist was used to capture all inclusion and exclusion criteria and verify that ...
TKRS_T0_ParticipantInfo TKRS_T0_ParticipantInfo Basic participant characteristics were collected using standardized study questionnaires and ...
TKRS_T0_Questionnaire TKRS_T0_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
TKRS_T1_CT TKRS_T1_CT Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, ...
TKRS_T1_DEXAAssessment TKRS_T1_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
TKRS_T1_GSRS TKRS_T1_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
TKRS_T1_PSQI TKRS_T1_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
TKRS_T1_SF36v2NL TKRS_T1_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
TKRS_T1_SFsarQoL TKRS_T1_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
TKRS_T1_WOMAC TKRS_T1_WOMAC The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants ...
TKRS_T1_Anthropometrics TKRS_T1_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
TKRS_T1_AtHome TKRS_T1_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
TKRS_T1_1RM TKRS_T1_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
TKRS_T1_BloodSampling TKRS_T1_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
TKRS_T1_Fam1RM TKRS_T1_Fam1RM Participants completed a familiarization session to learn correct exercise technique and become ...
TKRS_T1_PhysicalFunction TKRS_T1_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
TKRS_T1_Questionnaire TKRS_T1_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
TKRS_T1_Uni1RM TKRS_T1_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
TKRS_T1_Nutrition TKRS_T1_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
TKRS_T1_DEXA TKRS_T1_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
TKRS_T1_Nightingale TKRS_T1_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
TKRS_T1_GlucoseInsulinVitD TKRS_T1_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
TKRS_T2_CT TKRS_T2_CT Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, ...
TKRS_T2_DEXAAssessment TKRS_T2_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
TKRS_T2_GSRS TKRS_T2_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
TKRS_T2_PSQI TKRS_T2_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
TKRS_T2_SF36v2NL TKRS_T2_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
TKRS_T2_SFsarQoL TKRS_T2_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
TKRS_T2_WOMAC TKRS_T2_WOMAC The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants ...
TKRS_T2_Anthropometrics TKRS_T2_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
TKRS_T2_AtHome TKRS_T2_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
TKRS_T2_BloodSampling TKRS_T2_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
TKRS_T2_1RM TKRS_T2_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
TKRS_T2_PhysicalFunction TKRS_T2_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
TKRS_T2_Uni1RM TKRS_T2_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
TKRS_T2_Nutrition TKRS_T2_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
TKRS_T2_DEXA TKRS_T2_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
TKRS_T2_Nightingale TKRS_T2_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
TKRS_T2_GlucoseInsulinVitD TKRS_T2_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
TKRV_T0_MMSE TKRV_T0_MMSE Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test ...
TKRV_T0_SQUASH TKRV_T0_SQUASH The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, ...
TKRV_T0_Anthropometrics TKRV_T0_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
TKRV_T0_eGFR TKRV_T0_eGFR Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from ...
TKRV_T0_Eligibility TKRV_T0_Eligibility Participant eligibility for the study was determined based on medical criteria, functional ...
TKRV_T0_InExClusion TKRV_T0_InExClusion A checklist was used to capture all inclusion and exclusion criteria and verify that ...
TKRV_T0_ParticipantInfo TKRV_T0_ParticipantInfo Basic participant characteristics were collected using standardized study questionnaires and ...
TKRV_T0_Questionnaire TKRV_T0_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
TKRV_T1_CT TKRV_T1_CT Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, ...
TKRV_T1_DEXAAssessment TKRV_T1_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
TKRV_T1_GSRS TKRV_T1_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
TKRV_T1_PSQI TKRV_T1_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
TKRV_T1_SF36v2NL TKRV_T1_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
TKRV_T1_SFsarQoL TKRV_T1_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
TKRV_T1_WOMAC TKRV_T1_WOMAC The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants ...
TKRV_T1_Anthropometrics TKRV_T1_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
TKRV_T1_AtHome TKRV_T1_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
TKRV_T1_1RM TKRV_T1_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
TKRV_T1_BloodSampling TKRV_T1_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
TKRV_T1_Fam1RM TKRV_T1_Fam1RM Participants completed a familiarization session to learn correct exercise technique and become ...
TKRV_T1_PhysicalFunction TKRV_T1_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
TKRV_T1_Questionnaire TKRV_T1_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
TKRV_T1_Uni1RM TKRV_T1_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
TKRV_T1_Nutrition TKRV_T1_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
TKRV_T1_DEXA TKRV_T1_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
TKRV_T1_Nightingale TKRV_T1_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
TKRV_T1_GlucoseInsulinVitD TKRV_T1_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
TKRV_T2_CT TKRV_T2_CT Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, ...
TKRV_T2_DEXAAssessment TKRV_T2_DEXAAssessment administrative and quality control information related to the DXA assessment, including ...
TKRV_T2_GSRS TKRV_T2_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
TKRV_T2_PSQI TKRV_T2_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
TKRV_T2_SF36v2NL TKRV_T2_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
TKRV_T2_SFsarQoL TKRV_T2_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
TKRV_T2_WOMAC TKRV_T2_WOMAC The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants ...
TKRV_T2_Anthropometrics TKRV_T2_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
TKRV_T2_AtHome TKRV_T2_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
TKRV_T2_BloodSampling TKRV_T2_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
TKRV_T2_1RM TKRV_T2_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
TKRV_T2_PhysicalFunction TKRV_T2_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
TKRV_T2_Uni1RM TKRV_T2_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
TKRV_T2_Nutrition TKRV_T2_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
TKRV_T2_DEXA TKRV_T2_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
TKRV_T2_Nightingale TKRV_T2_Nightingale Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton ...
TKRV_T2_GlucoseInsulinVitD TKRV_T2_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
TKRV_dropouts_T0_MMSE TKRV_dropouts_T0_MMSE Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test ...
TKRV_dropouts_T0_SQUASH TKRV_dropouts_T0_SQUASH The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, ...
TKRV_dropouts_T0_Anthropometrics TKRV_dropouts_T0_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
TKRV_dropouts_T0_eGFR TKRV_dropouts_T0_eGFR Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from ...
TKRV_dropouts_T0_Eligibility TKRV_dropouts_T0_Eligibility Participant eligibility for the study was determined based on medical criteria, functional ...
TKRV_dropouts_T0_InExClusion TKRV_dropouts_T0_InExClusion A checklist was used to capture all inclusion and exclusion criteria and verify that ...
TKRV_dropouts_T0_ParticipantInfo TKRV_dropouts_T0_ParticipantInfo Basic participant characteristics were collected using standardized study questionnaires and ...
TKRV_dropouts_T0_Questionnaire TKRV_dropouts_T0_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
TKRV_dropouts_T1_CT TKRV_dropouts_T1_CT Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, ...
TKRV_dropouts_T1_DEXA TKRV_dropouts_T1_DEXA administrative and quality control information related to the DXA assessment, including ...
TKRV_dropouts_T1_GSRS TKRV_dropouts_T1_GSRS Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 ...
TKRV_dropouts_T1_PSQI TKRV_dropouts_T1_PSQI Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). ...
TKRV_dropouts_T1_SF36v2NL TKRV_dropouts_T1_SF36v2NL General health status was measured using the Dutch Version of the 36-Item Short Form Health ...
TKRV_dropouts_T1_SFsarQoL TKRV_dropouts_T1_SFsarQoL This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of ...
TKRV_dropouts_T1_WOMAC TKRV_dropouts_T1_WOMAC The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants ...
TKRV_dropouts_T1_Anthropometrics TKRV_dropouts_T1_Anthropometrics Standardized anthropometric measurements including height, body weight and waist circumference. ...
TKRV_dropouts_T1_AtHome TKRV_dropouts_T1_AtHome Metadata on whether participants completed the instructions for home-based study activities. ...
TKRV_dropouts_T1_1RM TKRV_dropouts_T1_1RM Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise ...
TKRV_dropouts_T1_BloodSampling TKRV_dropouts_T1_BloodSampling Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes ...
TKRV_dropouts_T1_Fam1RM TKRV_dropouts_T1_Fam1RM Participants completed a familiarization session to learn correct exercise technique and become ...
TKRV_dropouts_T1_PhysicalFunction TKRV_dropouts_T1_PhysicalFunction Includes standardized physical performances assessments such as Short Physical Performance ...
TKRV_dropouts_T1_Questionnaire TKRV_dropouts_T1_Questionnaire Participant-reported information was collected through study questionnaires. The questionnaires ...
TKRV_dropouts_T1_Uni1RM TKRV_dropouts_T1_Uni1RM Maximal muscle strength was assessed using unilateral one-repetition maximum testing on ...
TKRV_dropouts_T1_Nutrition TKRV_dropouts_T1_Nutrition Three-day food diary: Participants recorded all food and beverage intake for three complete, ...
TKRV_dropouts_T1_DEXA TKRV_dropouts_T1_DEXA Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants ...
TKRV_dropouts_T1_GlucoseInsulinVitD TKRV_dropouts_T1_GlucoseInsulinVitD Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted ...
BeatCovid_Info BeatCovid_Info Information on BEAT COVID samples
BeatCovid_LabMeasurements BeatCovid_LabMeasurements BEAT COVID Lab Measurements
BeatCovid_SeverityScores BeatCovid_SeverityScores BEAT COVID Severity Scores
BeatCovid_Viralct BeatCovid_Viralct BeatCovid Viral data
ProPark_AgeGender ProPark_AgeGender
ProPark_Axivity_info ProPark_Axivity_info ProPark_Axivity_info
ProPark_LEDD ProPark_LEDD LEDD
ProPark_Medication ProPark_Medication ProPark_Medication
Propark_Samples Propark_Samples Propark_Samples
ProPark_Study_long ProPark_Study_long ProPark study data in long format. De variabele "parent" is het moment van data verzamelen.
ProPark_Survey_long ProPark_Survey_long ProPark survey data in long format

LLS_G2_T1_Cellcounts

LLS G2 T1 Cellcounts

None

LLS_G3_T4_Castor_Balance_tests

Castor Balance tests

None

LLS_G3_T4_Castor_Blood_sampling

Castor Blood sampling

None

LLS_G3_T4_Castor_Cognitive_tests

Castor Cognitive tests

None

LLS_G3_T4_Castor_Medication_use

Castor Medication use

None

LLS_G3_T4_Castor_Medical_history_CCI

Castor Medical history CCI

None

LLS_G3_T4_Castor_Measurements_General

Castor Measurements General

None

LLS_G3_T4_Castor_Measurements_BIA_measurement

Castor Measurements BIA measurement

None

LLS_G3_T4_Castor_Measurements_Blood_pressure

Castor Measurements Blood pressure

None

LLS_G3_T4_Castor_Measurements_ECG

Castor Measurements ECG

None

LLS_G3_T4_Castor_Measurements_Grip_strength_test

Castor Measurements Grip strength test

None

LLS_G3_T4_Castor_Measurements_Lung_function

Castor Measurements Lung function

None

LLS_G3_T4_Castor_Scores_questionnaire_accidental

Castor Scores questionnaire accidental

None

LLS_G3_T4_Castor_Home_biomaterial

Castor Home biomaterial

None

LLS_G3_T4_Castor_Home_questionnaires

Castor Home questionnaires

None

LLS_G3_T4_Castor_Welcome

Castor Welcome

None

LLS_G2_T1_GutMicroBiomeRelated

LLS G2 T1 GutMicroBiomeRelated

None

LLS_G3_Q1_FFQ_Fooditems

LLS G3 Q1 FFQ Fooditems

None

LLS_G3_T4_Nightingale_2024

Nightingale 2024

None

LLS_G3_T4_survey_General_questionnaire_LLS

survey General questionnaire LLS

None

LLS_G3_T4_survey_Gastrointestinal_health_(GSRS)

survey Gastrointestinal health (GSRS)

None

LLS_G3_T4_survey_Physical_activity_(SQUASH)_OLD

survey Physical activity (SQUASH) OLD

None

LLS_G3_T4_survey_Physical_activity_(SQUASH)

survey Physical activity (SQUASH)

None

LLS_G3_T4_survey_Physical_function_ADL_IADL

survey Physical function ADL IADL

None

LLS_G3_T4_survey_Mood_and_behavior_(CES-D)

survey Mood and behavior (CES-D)

None

LLS_G3_T4_survey_Quality_of_life_(EQ-5D)

survey Quality of life (EQ-5D)

None

LLS_G3_T4_survey_Life_orientation_questionnaire

survey Life orientation questionnaire

None

LLS_G3_T4_Bloodcellcounts

Bloodcellcounts

None

LLS_G3_T4_survey_Food_frequency_questionnaire_(FFQ)

survey Food frequency questionnaire (FFQ)

None

LLS_G2_T1_NightingaleQL2020

LLS G2 T1 NightingaleQL2020

None

LLS_G3_T1_Blood_cellcounts

LLS G3 T1 Blood cellcounts

None

LLS_G3_T1_ClinicalChemistry

LLS G3 T1 ClinicalChemistry

None

LLS_G3_T1_Demography2024

LLS G3 T1 Demography2024

None

LLS_G3_T1_LeidenNMR_Kimble

LLS G3 T1 LeidenNMR Kimble

None

LLS_G3_T1_Nightingale_QL2020

LLS G3 T1 Nightingale QL2020

None

LLS_G3_T1_Participant_info

LLS G3 T1 Participant info

None

LLS_G2_T1_clinicalchemistry

LLS G2 T1 clinicalchemistry

None

LLS_G3_T2_Participant_info

LLS G3 T2 Participant info

None

LLS_G3_T2_BIA_Body_Composition

LLS G3 T2 BIA Body Composition

None

LLS_G3_T2_blood_pressure

LLS G3 T2 blood pressure

None

LLS_G3_T2_Clinical_chemistry

LLS G3 T2 Clinical chemistry

None

LLS_G3_T2_Gripstrength

LLS G3 T2 Gripstrength

None

LLS_G3_T2_Nightingale_QL16_20

LLS G3 T2 Nightingale QL16 20

None

LLS_G3_T3_Apolipoprotein_pltf

LLS G3 T3 Apolipoprotein pltf

None

LLS_G3_T3_Nightingale_QL16_20

LLS G3 T3 Nightingale QL16 20

None

LLS_G3_T3_OLINKcardiomatebolic_measures

LLS G3 T3 OLINKcardiomatebolic measures

None

LLS_G3_T3_OLINKcardiomatebolic_metadata

LLS G3 T3 OLINKcardiomatebolic metadata

None

LLS_G3_T3_OLINKcardiomatebolic_samples

LLS G3 T3 OLINKcardiomatebolic samples

None

LLS_G3_T3_Participant_info

LLS G3 T3 Participant info

None

LLS_G3_T3_Cognition_questions

LLS G3 T3 Cognition questions

None

LLS_G3_T3_Global_Metabolomics

LLS G3 T3 Global Metabolomics

None

LLS_G3_T3_Global_Metabolomics_Dictionary

LLS G3 T3 Global Metabolomics Dictionary

None

LLS_G3_T3_Global_Metabolomics_Overview

LLS G3 T3 Global Metabolomics Overview

None

LLS_G3_T3_IGF_axis

LLS G3 T3 IGF axis

None

LLS_G3_T3_MRI_Data

LLS G3 T3 MRI Data

None

LLS_G3_T3_Plasma_Amyloid_markers

LLS G3 T3 Plasma Amyloid markers

None

LLS_G3_T3_Plasma_endothelial_mrk

LLS G3 T3 Plasma endothelial mrk

None

LLS_G3_T3_SignalingLipids_Dictionary

LLS G3 T3 SignalingLipids Dictionary

None

LLS_G3_T3_SignalingLipids_Metabolomics

LLS G3 T3 SignalingLipids Metabolomics

None

LLS_G3_T3_SignalingLipids_Overview

LLS G3 T3 SignalingLipids Overview

None

LLS_G3_T3_Thyroid_measures

LLS G3 T3 Thyroid measures

None

LLS_G3_Q1_FFQ_Aminoacids

LLS G3 Q1 FFQ Aminoacids

None

LLS_G3_Q1_FFQ_Food_group_key

LLS G3 Q1 FFQ Food group key

None

LLS_G3_Q1_FFQ_Foodgroups_main

LLS G3 Q1 FFQ Foodgroups main

None

LLS_G3_Q1_FFQ_Foodgroups_sub

LLS G3 Q1 FFQ Foodgroups sub

None

LLS_G3_Q1_FFQ_key_food_groups_20200911

LLS G3 Q1 FFQ key food groups 20200911

None

LLS_G3_Q1_FFQ_Macronutrients

LLS G3 Q1 FFQ Macronutrients

None

LLS_G3_Q1_FFQ_Nevo2006

LLS G3 Q1 FFQ Nevo2006

None

LLS_G2_T1_NMR

LLS G2 T1 NMR

None

LLS_G2_T1_Participant_info

LLS G2 T1 Participant info

None

LLS_G2_T1_Visit_Measures

LLS G2 T1 Visit Measures

None

LLS_G2_T1_Demography

LLS G2 T1 Demography

None

LLS_G2_T1_LipoScience

LLS G2 T1 LipoScience

None

LLS_G2_T1_Demography2021

LLS G2 T1 Demography2021

None

LLS_G2_T1_SHARK_data

LLS G2 T1 SHARK data

None

LLS_G3_T1_Demography2021

LLS G3 T1 Demography2021

None

LLS_G3_T1_SHARK_data

LLS G3 T1 SHARK data

None

LLS_G3_T1_Epigenetic_predictors

LLS G3 T1 Epigenetic predictors

None

LLS_G3_T1_IgG_LC-MS

LLS G3 T1 IgG LC-MS

None

LLS_G3_T1_LipoScience

LLS G3 T1 LipoScience

None

MetC_T0_MMSE

MetC_T0_MMSE

Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test evaluated orientation, attention, memory, language, and visuospatial abilities on a 30-point scale. ...

MetC_T0_SQUASH

MetC_T0_SQUASH

The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, frequency, duration and intensity of physical activities across commuting household, work, and leisure ...

MetC_T0_Anthropometrics

MetC_T0_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MetC_T0_eGFR

MetC_T0_eGFR

Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from serum creatinine measurements using standard clinical laboratory equations. Licence: Creative ...

MetC_T0_Eligibility

MetC_T0_Eligibility

Participant eligibility for the study was determined based on medical criteria, functional assessments, planned knee surgery, rehabilitation plans, and metabolomics/mortality-related data. ...

MetC_T0_InExClusion

MetC_T0_InExClusion

A checklist was used to capture all inclusion and exclusion criteria and verify that participants met them. Licence: Creative Commons Attribution 4.0 International (CC-BY 4.0)

MetC_T0_ParticipantInfo

MetC_T0_ParticipantInfo

Basic participant characteristics were collected using standardized study questionnaires and recorded in the electronic case report form (Castor EDC) Licence: Creative Commons Attribution 4.0 ...

MetC_T0_Questionnaire

MetC_T0_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

MetC_T1_DEXAAssessment

MetC_T1_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

MetC_T1_GSRS

MetC_T1_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

MetC_T1_PSQI

MetC_T1_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

MetC_T1_SF36v2NL

MetC_T1_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

MetC_T1_SFsarQoL

MetC_T1_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

MetC_T1_Anthropometrics

MetC_T1_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MetC_T1_AtHome

MetC_T1_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

MetC_T1_Base1RM

MetC_T1_Base1RM

Maximal muscle strength was assessed at baseline using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the ...

MetC_T1_BloodSampling

MetC_T1_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

MetC_T1_Fam1RM

MetC_T1_Fam1RM

Participants completed a familiarization session to learn correct exercise technique and become accustomed to the resistance training equipment. During this session, an estimated one-repetition ...

MetC_T1_PhysicalFunction

MetC_T1_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

MetC_T1_Questionnaire

MetC_T1_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

MetC_T1_1RM

MetC_T1_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

MetC_T1_Nutrition

MetC_T1_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

MetC_T1_DEXA

MetC_T1_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

MetC_T1_Nightingale

MetC_T1_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

MetC_T1_GlucoseInsulinVitD

MetC_T1_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

MetC_T2_DEXAAssessment

MetC_T2_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

MetC_T2_GSRS

MetC_T2_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

MetC_T2_PSQI

MetC_T2_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

MetC_T2_SF36v2NL

MetC_T2_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

MetC_T2_SFsarQoL

MetC_T2_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

MetC_T2_Anthropometrics

MetC_T2_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MetC_T2_AtHome

MetC_T2_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

MetC_T2_BloodSampling

MetC_T2_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

MetC_T2_1RM

MetC_T2_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

MetC_T2_PhysicalFunction

MetC_T2_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

MetC_T2_Uni1RM

MetC_T2_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

MetC_T2_Nutrition

MetC_T2_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

MetC_T2_DEXA

MetC_T2_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

MetC_T2_Nightingale

MetC_T2_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

MetC_T2_GlucoseInsulinVitD

MetC_T2_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

MetC_dropouts_T0_MMSE

MetC_dropouts_T0_MMSE

Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test evaluated orientation, attention, memory, language, and visuospatial abilities on a 30-point scale. ...

MetC_dropouts_T0_SQUASH

MetC_dropouts_T0_SQUASH

The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, frequency, duration and intensity of physical activities across commuting household, work, and leisure ...

MetC_dropouts_T0_Anthropometrics

MetC_dropouts_T0_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MetC_dropouts_T0_eGFR

MetC_dropouts_T0_eGFR

Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from serum creatinine measurements using standard clinical laboratory equations. Licence: Creative ...

MetC_dropouts_T0_Eligibility

MetC_dropouts_T0_Eligibility

Participant eligibility for the study was determined based on medical criteria, functional assessments, planned knee surgery, rehabilitation plans, and metabolomics/mortality-related data. ...

MetC_dropouts_T0_InExClusion

MetC_dropouts_T0_InExClusion

A checklist was used to capture all inclusion and exclusion criteria and verify that participants met them. Licence: Creative Commons Attribution 4.0 International (CC-BY 4.0)

MetC_dropouts_T0_ParticipantInfo

MetC_dropouts_T0_ParticipantInfo

Basic participant characteristics were collected using standardized study questionnaires and recorded in the electronic case report form (Castor EDC) Licence: Creative Commons Attribution 4.0 ...

MetC_dropouts_T0_Questionnaire

MetC_dropouts_T0_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

MetC_dropouts_T1_DEXAAssessment

MetC_dropouts_T1_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

MetC_dropouts_T1_GSRS

MetC_dropouts_T1_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

MetC_dropouts_T1_PSQI

MetC_dropouts_T1_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

MetC_dropouts_T1_SF36v2NL

MetC_dropouts_T1_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

MetC_dropouts_T1_SFsarQoL

MetC_dropouts_T1_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

MetC_dropouts_T1_Anthropometrics

MetC_dropouts_T1_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MetC_dropouts_T1_AtHome

MetC_dropouts_T1_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

MetC_dropouts_T1_1RM

MetC_dropouts_T1_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

MetC_dropouts_T1_BloodSampling

MetC_dropouts_T1_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

MetC_dropouts_T1_Fam1RM

MetC_dropouts_T1_Fam1RM

Participants completed a familiarization session to learn correct exercise technique and become accustomed to the resistance training equipment. During this session, an estimated one-repetition ...

MetC_dropouts_T1_PhysicalFunction

MetC_dropouts_T1_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

MetC_dropouts_T1_Questionnaire

MetC_dropouts_T1_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

MetC_dropouts_T1_Nutrition

MetC_dropouts_T1_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

MetC_dropouts_T1_DEXA

MetC_dropouts_T1_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

MetC_dropouts_T1_GlucoseInsulinVitD

MetC_dropouts_T1_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

MobC_T0_MMSE

MobC_T0_MMSE

Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test evaluated orientation, attention, memory, language, and visuospatial abilities on a 30-point scale. ...

MobC_T0_SQUASH

MobC_T0_SQUASH

The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, frequency, duration and intensity of physical activities across commuting household, work, and leisure ...

MobC_T0_Anthropometrics

MobC_T0_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MobC_T0_eGFR

MobC_T0_eGFR

Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from serum creatinine measurements using standard clinical laboratory equations. Licence: Creative ...

MobC_T0_Eligibility

MobC_T0_Eligibility

Participant eligibility for the study was determined based on medical criteria, functional assessments, planned knee surgery, rehabilitation plans, and metabolomics/mortality-related data. ...

MobC_T0_InExClusion

MobC_T0_InExClusion

A checklist was used to capture all inclusion and exclusion criteria and verify that participants met them. Licence: Creative Commons Attribution 4.0 International (CC-BY 4.0)

MobC_T0_ParticipantInfo

MobC_T0_ParticipantInfo

Basic participant characteristics were collected using standardized study questionnaires and recorded in the electronic case report form (Castor EDC) Licence: Creative Commons Attribution 4.0 ...

MobC_T0_Questionnaire

MobC_T0_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

MobC_T1_DEXAAssessment

MobC_T1_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

MobC_T1_GSRS

MobC_T1_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

MobC_T1_PSQI

MobC_T1_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

MobC_T1_SF36v2NL

MobC_T1_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

MobC_T1_SFsarQoL

MobC_T1_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

MobC_T1_Anthropometrics

MobC_T1_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MobC_T1_AtHome

MobC_T1_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

MobC_T1_1RM

MobC_T1_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

MobC_T1_BloodSampling

MobC_T1_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

MobC_T1_Fam1RM

MobC_T1_Fam1RM

Participants completed a familiarization session to learn correct exercise technique and become accustomed to the resistance training equipment. During this session, an estimated one-repetition ...

MobC_T1_PhysicalFunction

MobC_T1_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

MobC_T1_Questionnaire

MobC_T1_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

MobC_T1_Uni1RM

MobC_T1_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

MobC_T1_Nutrition

MobC_T1_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

MobC_T1_DEXA

MobC_T1_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

MobC_T1_Nightingale

MobC_T1_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

MobC_T1_GlucoseInsulinVitD

MobC_T1_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

MobC_T2_DEXAAssessment

MobC_T2_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

MobC_T2_GSRS

MobC_T2_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

MobC_T2_PSQI

MobC_T2_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

MobC_T2_SF36v2NL

MobC_T2_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

MobC_T2_SFsarQoL

MobC_T2_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

MobC_T2_Anthropometrics

MobC_T2_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MobC_T2_AtHome

MobC_T2_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

MobC_T2_BloodSampling

MobC_T2_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

MobC_T2_1RM

MobC_T2_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

MobC_T2_PhysicalFunction

MobC_T2_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

MobC_T2_Uni1RM

MobC_T2_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

MobC_T2_Nutrition

MobC_T2_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

MobC_T2_DEXA

MobC_T2_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

MobC_T2_Nightingale

MobC_T2_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

MobC_T2_GlucoseInsulinVitD

MobC_T2_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

MobC_dropouts_T0_MMSE

MobC_dropouts_T0_MMSE

Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test evaluated orientation, attention, memory, language, and visuospatial abilities on a 30-point scale. ...

MobC_dropouts_T0_SQUASH

MobC_dropouts_T0_SQUASH

The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, frequency, duration and intensity of physical activities across commuting household, work, and leisure ...

MobC_dropouts_T0_Anthropometrics

MobC_dropouts_T0_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MobC_dropouts_T0_eGFR

MobC_dropouts_T0_eGFR

Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from serum creatinine measurements using standard clinical laboratory equations. Licence: Creative ...

MobC_dropouts_T0_Eligibility

MobC_dropouts_T0_Eligibility

Participant eligibility for the study was determined based on medical criteria, functional assessments, planned knee surgery, rehabilitation plans, and metabolomics/mortality-related data. ...

MobC_dropouts_T0_InExClusion

MobC_dropouts_T0_InExClusion

A checklist was used to capture all inclusion and exclusion criteria and verify that participants met them. Licence: Creative Commons Attribution 4.0 International (CC-BY 4.0)

MobC_dropouts_T0_ParticipantInfo

MobC_dropouts_T0_ParticipantInfo

Basic participant characteristics were collected using standardized study questionnaires and recorded in the electronic case report form (Castor EDC) Licence: Creative Commons Attribution 4.0 ...

MobC_dropouts_T0_Questionnaire

MobC_dropouts_T0_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

MobC_dropouts_T1_DEXAAssessment

MobC_dropouts_T1_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

MobC_dropouts_T1_GSRS

MobC_dropouts_T1_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

MobC_dropouts_T1_PSQI

MobC_dropouts_T1_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

MobC_dropouts_T1_SF36v2NL

MobC_dropouts_T1_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

MobC_dropouts_T1_SFsarQol

MobC_dropouts_T1_SFsarQol

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

MobC_dropouts_T1_Anthropometrics

MobC_dropouts_T1_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

MobC_dropouts_T1_AtHome

MobC_dropouts_T1_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

MobC_dropouts_T1_1RM

MobC_dropouts_T1_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

MobC_dropouts_T1_BloodSampling

MobC_dropouts_T1_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

MobC_dropouts_T1_Fam1RM

MobC_dropouts_T1_Fam1RM

Participants completed a familiarization session to learn correct exercise technique and become accustomed to the resistance training equipment. During this session, an estimated one-repetition ...

MobC_dropouts_T1_PhysicalFunction

MobC_dropouts_T1_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

MobC_dropouts_T1_Questionnaire

MobC_dropouts_T1_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

MobC_dropouts_T1_Uni1RM

MobC_dropouts_T1_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

MobC_dropouts_T1_Nutrition

MobC_dropouts_T1_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

MobC_dropouts_T1_DEXA

MobC_dropouts_T1_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

MobC_dropouts_T1_GlucoseInsulinVitD

MobC_dropouts_T1_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

REF_T0_MMSE

REF_T0_MMSE

Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test evaluated orientation, attention, memory, language, and visuospatial abilities on a 30-point scale. ...

REF_T0_SQUASH

REF_T0_SQUASH

The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, frequency, duration and intensity of physical activities across commuting household, work, and leisure ...

REF_T0_Anthropometrics

REF_T0_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

REF_T0_eGFR

REF_T0_eGFR

Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from serum creatinine measurements using standard clinical laboratory equations. Licence: Creative ...

REF_T0_Eligibility

REF_T0_Eligibility

Participant eligibility for the study was determined based on medical criteria, functional assessments, planned knee surgery, rehabilitation plans, and metabolomics/mortality-related data. ...

REF_T0_InExClusion

REF_T0_InExClusion

A checklist was used to capture all inclusion and exclusion criteria and verify that participants met them. Licence: Creative Commons Attribution 4.0 International (CC-BY 4.0)

REF_T0_ParticipantInfo

REF_T0_ParticipantInfo

Basic participant characteristics were collected using standardized study questionnaires and recorded in the electronic case report form (Castor EDC) Licence: Creative Commons Attribution 4.0 ...

REF_T0_Questionnaire

REF_T0_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

REF_T1_DEXAAssessment

REF_T1_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

REF_T1_GSRS

REF_T1_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

REF_T1_PSQI

REF_T1_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

REF_T1_SF36v2NL

REF_T1_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

REF_T1_SFsarQoL

REF_T1_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

REF_T1_Anthropometrics

REF_T1_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

REF_T1_AtHome

REF_T1_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

REF_T1_1RM

REF_T1_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

REF_T1_BloodSampling

REF_T1_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

REF_T1_Fam1RM

REF_T1_Fam1RM

Participants completed a familiarization session to learn correct exercise technique and become accustomed to the resistance training equipment. During this session, an estimated one-repetition ...

REF_T1_PhysicalFunction

REF_T1_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

REF_T1_Questionnaire

REF_T1_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

REF_T1_Uni1RM

REF_T1_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

REF_T1_Nutrition

REF_T1_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

REF_T1_DEXA

REF_T1_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

REF_T1_Nightingale

REF_T1_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

REF_T1_GlucoseInsulinVitD

REF_T1_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

TKRS_T0_MMSE

TKRS_T0_MMSE

Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test evaluated orientation, attention, memory, language, and visuospatial abilities on a 30-point scale. ...

TKRS_T0_SQUASH

TKRS_T0_SQUASH

The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, frequency, duration and intensity of physical activities across commuting household, work, and leisure ...

TKRS_T0_Anthropometrics

TKRS_T0_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

TKRS_T0_eGFR

TKRS_T0_eGFR

Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from serum creatinine measurements using standard clinical laboratory equations. Licence: Creative ...

TKRS_T0_Eligibility

TKRS_T0_Eligibility

Participant eligibility for the study was determined based on medical criteria, functional assessments, planned knee surgery, rehabilitation plans, and metabolomics/mortality-related data. ...

TKRS_T0_InExClusion

TKRS_T0_InExClusion

A checklist was used to capture all inclusion and exclusion criteria and verify that participants met them. Licence: Creative Commons Attribution 4.0 International (CC-BY 4.0)

TKRS_T0_ParticipantInfo

TKRS_T0_ParticipantInfo

Basic participant characteristics were collected using standardized study questionnaires and recorded in the electronic case report form (Castor EDC) Licence: Creative Commons Attribution 4.0 ...

TKRS_T0_Questionnaire

TKRS_T0_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

TKRS_T1_CT

TKRS_T1_CT

Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, distance from the patella, distance from the scanner, and other relevant scan parameters. Measurement ...

TKRS_T1_DEXAAssessment

TKRS_T1_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

TKRS_T1_GSRS

TKRS_T1_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

TKRS_T1_PSQI

TKRS_T1_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

TKRS_T1_SF36v2NL

TKRS_T1_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

TKRS_T1_SFsarQoL

TKRS_T1_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

TKRS_T1_WOMAC

TKRS_T1_WOMAC

The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants undergoing total knee replacement to assess osteoarthritis-related symptoms. The questionnaire ...

TKRS_T1_Anthropometrics

TKRS_T1_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

TKRS_T1_AtHome

TKRS_T1_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

TKRS_T1_1RM

TKRS_T1_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

TKRS_T1_BloodSampling

TKRS_T1_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

TKRS_T1_Fam1RM

TKRS_T1_Fam1RM

Participants completed a familiarization session to learn correct exercise technique and become accustomed to the resistance training equipment. During this session, an estimated one-repetition ...

TKRS_T1_PhysicalFunction

TKRS_T1_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

TKRS_T1_Questionnaire

TKRS_T1_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

TKRS_T1_Uni1RM

TKRS_T1_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

TKRS_T1_Nutrition

TKRS_T1_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

TKRS_T1_DEXA

TKRS_T1_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

TKRS_T1_Nightingale

TKRS_T1_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

TKRS_T1_GlucoseInsulinVitD

TKRS_T1_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

TKRS_T2_CT

TKRS_T2_CT

Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, distance from the patella, distance from the scanner, and other relevant scan parameters. Measurement ...

TKRS_T2_DEXAAssessment

TKRS_T2_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

TKRS_T2_GSRS

TKRS_T2_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

TKRS_T2_PSQI

TKRS_T2_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

TKRS_T2_SF36v2NL

TKRS_T2_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

TKRS_T2_SFsarQoL

TKRS_T2_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

TKRS_T2_WOMAC

TKRS_T2_WOMAC

The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants undergoing total knee replacement to assess osteoarthritis-related symptoms. The questionnaire ...

TKRS_T2_Anthropometrics

TKRS_T2_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

TKRS_T2_AtHome

TKRS_T2_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

TKRS_T2_BloodSampling

TKRS_T2_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

TKRS_T2_1RM

TKRS_T2_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

TKRS_T2_PhysicalFunction

TKRS_T2_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

TKRS_T2_Uni1RM

TKRS_T2_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

TKRS_T2_Nutrition

TKRS_T2_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

TKRS_T2_DEXA

TKRS_T2_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

TKRS_T2_Nightingale

TKRS_T2_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

TKRS_T2_GlucoseInsulinVitD

TKRS_T2_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

TKRV_T0_MMSE

TKRV_T0_MMSE

Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test evaluated orientation, attention, memory, language, and visuospatial abilities on a 30-point scale. ...

TKRV_T0_SQUASH

TKRV_T0_SQUASH

The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, frequency, duration and intensity of physical activities across commuting household, work, and leisure ...

TKRV_T0_Anthropometrics

TKRV_T0_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

TKRV_T0_eGFR

TKRV_T0_eGFR

Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from serum creatinine measurements using standard clinical laboratory equations. Licence: Creative ...

TKRV_T0_Eligibility

TKRV_T0_Eligibility

Participant eligibility for the study was determined based on medical criteria, functional assessments, planned knee surgery, rehabilitation plans, and metabolomics/mortality-related data. ...

TKRV_T0_InExClusion

TKRV_T0_InExClusion

A checklist was used to capture all inclusion and exclusion criteria and verify that participants met them. Licence: Creative Commons Attribution 4.0 International (CC-BY 4.0)

TKRV_T0_ParticipantInfo

TKRV_T0_ParticipantInfo

Basic participant characteristics were collected using standardized study questionnaires and recorded in the electronic case report form (Castor EDC) Licence: Creative Commons Attribution 4.0 ...

TKRV_T0_Questionnaire

TKRV_T0_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

TKRV_T1_CT

TKRV_T1_CT

Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, distance from the patella, distance from the scanner, and other relevant scan parameters. Measurement ...

TKRV_T1_DEXAAssessment

TKRV_T1_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

TKRV_T1_GSRS

TKRV_T1_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

TKRV_T1_PSQI

TKRV_T1_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

TKRV_T1_SF36v2NL

TKRV_T1_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

TKRV_T1_SFsarQoL

TKRV_T1_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

TKRV_T1_WOMAC

TKRV_T1_WOMAC

The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants undergoing total knee replacement to assess osteoarthritis-related symptoms. The questionnaire ...

TKRV_T1_Anthropometrics

TKRV_T1_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

TKRV_T1_AtHome

TKRV_T1_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

TKRV_T1_1RM

TKRV_T1_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

TKRV_T1_BloodSampling

TKRV_T1_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

TKRV_T1_Fam1RM

TKRV_T1_Fam1RM

Participants completed a familiarization session to learn correct exercise technique and become accustomed to the resistance training equipment. During this session, an estimated one-repetition ...

TKRV_T1_PhysicalFunction

TKRV_T1_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

TKRV_T1_Questionnaire

TKRV_T1_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

TKRV_T1_Uni1RM

TKRV_T1_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

TKRV_T1_Nutrition

TKRV_T1_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

TKRV_T1_DEXA

TKRV_T1_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

TKRV_T1_Nightingale

TKRV_T1_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

TKRV_T1_GlucoseInsulinVitD

TKRV_T1_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

TKRV_T2_CT

TKRV_T2_CT

Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, distance from the patella, distance from the scanner, and other relevant scan parameters. Measurement ...

TKRV_T2_DEXAAssessment

TKRV_T2_DEXAAssessment

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

TKRV_T2_GSRS

TKRV_T2_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

TKRV_T2_PSQI

TKRV_T2_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

TKRV_T2_SF36v2NL

TKRV_T2_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

TKRV_T2_SFsarQoL

TKRV_T2_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

TKRV_T2_WOMAC

TKRV_T2_WOMAC

The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants undergoing total knee replacement to assess osteoarthritis-related symptoms. The questionnaire ...

TKRV_T2_Anthropometrics

TKRV_T2_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

TKRV_T2_AtHome

TKRV_T2_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

TKRV_T2_BloodSampling

TKRV_T2_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

TKRV_T2_1RM

TKRV_T2_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

TKRV_T2_PhysicalFunction

TKRV_T2_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

TKRV_T2_Uni1RM

TKRV_T2_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

TKRV_T2_Nutrition

TKRV_T2_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

TKRV_T2_DEXA

TKRV_T2_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

TKRV_T2_Nightingale

TKRV_T2_Nightingale

Fasting blood samples (350ul) were analysed using the Nightingale Health high-throughput proton nuclear magnetic resonance (NMR) metabolomics platform. The platform quantified a broad panel of ...

TKRV_T2_GlucoseInsulinVitD

TKRV_T2_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

TKRV_dropouts_T0_MMSE

TKRV_dropouts_T0_MMSE

Global cognitive function was assessed using the Mini Mental State Examination (MMSE). The test evaluated orientation, attention, memory, language, and visuospatial abilities on a 30-point scale. ...

TKRV_dropouts_T0_SQUASH

TKRV_dropouts_T0_SQUASH

The Short Questionnaire to ASses Health-enhancing physical activity (SQUASH) measures type, frequency, duration and intensity of physical activities across commuting household, work, and leisure ...

TKRV_dropouts_T0_Anthropometrics

TKRV_dropouts_T0_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

TKRV_dropouts_T0_eGFR

TKRV_dropouts_T0_eGFR

Kidney function was assessed using estimated glomerular filtration rate (eGFR), calculated from serum creatinine measurements using standard clinical laboratory equations. Licence: Creative ...

TKRV_dropouts_T0_Eligibility

TKRV_dropouts_T0_Eligibility

Participant eligibility for the study was determined based on medical criteria, functional assessments, planned knee surgery, rehabilitation plans, and metabolomics/mortality-related data. ...

TKRV_dropouts_T0_InExClusion

TKRV_dropouts_T0_InExClusion

A checklist was used to capture all inclusion and exclusion criteria and verify that participants met them. Licence: Creative Commons Attribution 4.0 International (CC-BY 4.0)

TKRV_dropouts_T0_ParticipantInfo

TKRV_dropouts_T0_ParticipantInfo

Basic participant characteristics were collected using standardized study questionnaires and recorded in the electronic case report form (Castor EDC) Licence: Creative Commons Attribution 4.0 ...

TKRV_dropouts_T0_Questionnaire

TKRV_dropouts_T0_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

TKRV_dropouts_T1_CT

TKRV_dropouts_T1_CT

Metadata of the computed tomography (CT) scan of the knee, including scan date, bed height, distance from the patella, distance from the scanner, and other relevant scan parameters. Measurement ...

TKRV_dropouts_T1_DEXA

TKRV_dropouts_T1_DEXA

administrative and quality control information related to the DXA assessment, including participant preparation, scan completion, and assessment date. Measurement devices: Ref + MetC: Hologic ...

TKRV_dropouts_T1_GSRS

TKRV_dropouts_T1_GSRS

Gastrointestinal symptoms were assessed using the GSRS questionnaire. The instrument includes 15 items evaluating five symptom clusters, each rated on a 7-point Likert scale. ...

TKRV_dropouts_T1_PSQI

TKRV_dropouts_T1_PSQI

Sleep quality over the past month was assessed using the Pittsburgh Sleep Quality Index (PSQI). The questionnaire evaluated multiple aspects of sleep including sleep duration, disturbances, ...

TKRV_dropouts_T1_SF36v2NL

TKRV_dropouts_T1_SF36v2NL

General health status was measured using the Dutch Version of the 36-Item Short Form Health Survey (SF-36). This questionnaires measures eight domains including, physical functioning, role ...

TKRV_dropouts_T1_SFsarQoL

TKRV_dropouts_T1_SFsarQoL

This Short Form-Sarcopenia & Quality of Life questionnaire (SF-SarQol) evaluated the impact of sarcopenia on daily functioning, physical health, and well-being. ...

TKRV_dropouts_T1_WOMAC

TKRV_dropouts_T1_WOMAC

The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was used in participants undergoing total knee replacement to assess osteoarthritis-related symptoms. The questionnaire ...

TKRV_dropouts_T1_Anthropometrics

TKRV_dropouts_T1_Anthropometrics

Standardized anthropometric measurements including height, body weight and waist circumference. Height was measured to the nearest centimetre using a SECA stadiometer and body weight to the ...

TKRV_dropouts_T1_AtHome

TKRV_dropouts_T1_AtHome

Metadata on whether participants completed the instructions for home-based study activities. This includes information on the collection of fecal sampljes, use of accelerometers, and completion of ...

TKRV_dropouts_T1_1RM

TKRV_dropouts_T1_1RM

Maximal muscle strength was assessed using one-repetition maximum testing on resistance exercise machines. Participants performed progressively heavier single repetitions until the maximal load ...

TKRV_dropouts_T1_BloodSampling

TKRV_dropouts_T1_BloodSampling

Fasted blood samples were collected via venepuncture. Whole blood was collected in EDTA tubes for HbA1c analysis. Serum samples were processed locally for vitamin D and metabolomics analyses. ...

TKRV_dropouts_T1_Fam1RM

TKRV_dropouts_T1_Fam1RM

Participants completed a familiarization session to learn correct exercise technique and become accustomed to the resistance training equipment. During this session, an estimated one-repetition ...

TKRV_dropouts_T1_PhysicalFunction

TKRV_dropouts_T1_PhysicalFunction

Includes standardized physical performances assessments such as Short Physical Performance Battery (SPPB;balance, gait speed, and chair stand), Timed Up and Go (TUG), 6-minute walk test, and ...

TKRV_dropouts_T1_Questionnaire

TKRV_dropouts_T1_Questionnaire

Participant-reported information was collected through study questionnaires. The questionnaires captured various aspects of participants characteristics, health status, lifestyle factors, and ...

TKRV_dropouts_T1_Uni1RM

TKRV_dropouts_T1_Uni1RM

Maximal muscle strength was assessed using unilateral one-repetition maximum testing on resistance exercise machines. Strength was measured separately for each limb at baseline and endline. ...

TKRV_dropouts_T1_Nutrition

TKRV_dropouts_T1_Nutrition

Three-day food diary: Participants recorded all food and beverage intake for three complete, randomly selected days during the assessment week. The diaries were reviewed by a trained researcher or ...

TKRV_dropouts_T1_DEXA

TKRV_dropouts_T1_DEXA

Whole-body composition was measured using dual-energy X-ray absorptiometry (DXA). Participants were scanned in a fasted state while wearing light clothing. The scan provided measurements of ...

TKRV_dropouts_T1_GlucoseInsulinVitD

TKRV_dropouts_T1_GlucoseInsulinVitD

Fasting EDTA plasma samples were analysed to determine glucose and insulinconcentrations. Fasted serum samples were used to determine 25-hydroxyvitamin D concentrations. These measurements were ...

BeatCovid_Info

BeatCovid_Info

Information on BEAT COVID samples

BeatCovid_LabMeasurements

BeatCovid_LabMeasurements

BEAT COVID Lab Measurements

BeatCovid_SeverityScores

BeatCovid_SeverityScores

BEAT COVID Severity Scores

BeatCovid_Viralct

BeatCovid_Viralct

BeatCovid Viral data

ProPark_AgeGender

ProPark_AgeGender

ProPark_Axivity_info

ProPark_Axivity_info

ProPark_Axivity_info

ProPark_LEDD

ProPark_LEDD

LEDD

ProPark_Medication

ProPark_Medication

ProPark_Medication

Propark_Samples

Propark_Samples

Propark_Samples

ProPark_Study_long

ProPark_Study_long

ProPark study data in long format. De variabele "parent" is het moment van data verzamelen.

ProPark_Survey_long

ProPark_Survey_long

ProPark survey data in long format